Scientific Programme
Tuesday, 13th Wednesday, 14th Thursday, 15th Friday, 16th Saturday, 17th
Tuesday 13.9.2011 Introductory Course on Glial Biology |
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| Panorama Hall | |
| Chair: | Miroslava Anderova (Czech Republic) |
| 9.00 - 9.45 | Alexei Verkhratsky (UK) – Where the thoughts dwell: History of neuroscience and introduction into neuroglia |
| 9.45 - 10.30 | Helmut Kettenmann (Germany) – Microglia |
| 10.30 - 11.00 | Coffee break |
| 11.00 - 11.45 | Jose Julio Rodriguez Arellano (Spain) – Neuroglial role in the development and progress of Alzheimer´s disease: from God to Evil. |
| 11.45 - 12.30 | Florence Perrin (Spain) – Glial cells in spinal cord injury: towards clinical application |
| 12.30 - 13.30 | Lunch break |
| 13.30 - 14.15 | Nathalie Rouach (France) – Role of astrocytes in neurotransmission and plasticity |
| 14.15 - 15.00 | Selva Baltan (USA) – The role of oligodendrocytes in preserving axon function |
| 15.00 - 15.30 | Coffee break |
| 15.30 - 16.15 | Kristjan R. Jessen (UK) – Schwann cell biology |
| 16.15 - 17.00 | Arthur Butt (UK) – NG2-glia: novel glia with multiple functions? |
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Wednesday 14.9. 2011 |
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9.00 - 10.00 |
Plenary lecture 1 |
| Forum Hall | |
| Introduced by Pierre Magistretti (Switzerland) | |
| Maiken Nedergaard (USA) – Complexity of human astrocytes | |
| 10.00 - 10.30 | Coffee break |
| 10.30 - 12.30 | Symposium 1 - Functional roles of channels, receptors and synapses of NG2 cells |
| Panorama Hall | |
| Chairs: | María Cecilia Angulo (France), Christian Steinhäuser (Germany) |
| Speakers: | Dwight Bergles (USA) - Developmental changes in excitability and synaptic signaling in NG2 cells |
| Christian Steinhäuser (Germany) - Calcium signalling pathways and process motility in NG2 cells. | |
| María Cecilia Angulo (France) - Oligodendrocyte precursor cells (OPCs) of the grey matter are not only progenitors | |
| Maria Kukley (Germany) - Do synapses on NG2 cells regulate proliferation? | |
| Symposium 2 - Reactive astrocytes in neurotrauma and stroke | |
| Forum Hall | |
| Chairs: | Milos Pekny (Sweden), Michael Chopp (USA) |
| Speakers: | Milos Pekny (Sweden) - Reactive gliosis in CNS pathologies |
| Michael Chopp (USA) - Astrocytes in brain remodeling after stroke and trauma | |
| Michael Nilsson (Sweden) - Astrocytes and reaction to cellular stress in the CNS | |
| Ted Teng (USA) - Modulation of reactive gliosis and neural restoration in spinal cord injury | |
| Symposium 3 - Glial control of brain vasculature in health and disease | |
| Meeting Hall I | |
| Chairs: | Christian Lohr (Germany), Brian MacVicar (Canada) |
| Speakers: | Brian MacVicar (Canada) - Astrocyte modulation of cerebral blood vessels in health and disease |
| Richard Daneman (USA) - Molecular Mechanisms of Blood-Brain Barrier Regulation during Health and Disease | |
| Mark Nelson (USA) - The impact of astrocytic calcium signaling on brain arteriolar function | |
| Christian Lohr (Germany) - Extrasynaptic axon-glia communication and its role in neurovascular coupling | |
| Symposium 4 - Immune-mediated destruction of glial cells: mechanisms and consequences | |
| Meeting Hall IV | |
| Chairs: | Ari Waisman (Germany), Roland Liblau (France) |
| Speakers: | Ari Waisman (Germany) - Mechanisms of oligodendrocyte death in animal models of MS |
| Roland Liblau (France) - Animal models of CNS autoimmunity: glial vs neuronal targetting | |
| Burkhard Becher (Switzerland) - The role of cytokines in myelin damage | |
| Klaus-Armin Nave (Germany) - Oligodendrocyte defects causing inflammatory demyelination in mice | |
| Workshop 1 - Volume transmission and glia in pathophysiological states | |
| Meeting Hall V | |
| Chairs: | Lydia Vargova (Czech Republic), Sabina Hrabetova (USA) |
| Speakers: | Lydia Vargova (Czech Republic) - Glia and extracellular matrix changes affect extracellular diffusion and volume transmission in the brain in health and disease |
| Douglas Fields (USA) - Activity-dependent, non-synaptic release of neurotransmitter from axons in axon-glia communication | |
| Sabina Hrabetova (USA) - Extracellular matrix and charge discrimination in brain extracellular space | |
| Dmitri Rusakov (UK) - Astroglial coverage and functional plasticity of synapses | |
| 13.00 - 13.30 | Special lecture - Sponsored by Visual Sonic/Biotech   |
| Meeting Hall I | |
| Phillippe Trochet (Canada) - Functional brain imaging: latest developments in preclinical research | |
| 12.30 - 13.30 | Lunch break |
| 13.00 - 15.30 | Special event (by invitation only) |
| Holiday Inn hotel | |
| GLIA Editorial Board Meeting | |
| 13.30 - 15.30 | Poster Session/Exhibition |
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| 14.30 - 15.30 | Special event - Iberoamerican Glial Network Meeting |
| Panorama Hall | |
| 15.00 - 15.30 | Coffee break |
| 15.30 - 17.30 | Symposium 5 – Glycogen in physiology and pathophysiology |
| Panorama Hall | |
| Chairs: | Arne Schousboe (Denmark), Bruce Ransom (USA) |
| Speakers: | Pierre Magistretti (Switzerland) - Thirty years of glycogen studies in the brain |
| Bruce Ransom (USA) - Glycogen in Optic Nerve Function: Lessons Learned | |
| Arne Schousboe (Denmark) - Glycogen and glutamatergic transmission | |
| Gerald Dienel (USA) - Glycogen and glycolytic supercompensation in brain activity | |
| Symposium 6 – Olfactory ensheathing cells: the numerous roles in development and regeneration | |
| Meeting Hall V | |
| Chairs: | James St John (Australia), Cheng He (China) |
| Speakers: | Cheng He (China) - Molecular regulation of olfactory ensheathing cell migration |
| Inn Chuah (Australia) - Anti-bacterial properties of olfactory ensheathing cells | |
| Clare Baker (UK) - Development of olfactory ensheathing cells from the neural crest | |
| James St John (Australia) - Olfactory ensheathing cells: how different subpopulations regulate axon guidance | |
| Symposium 7 – The influence of glycosaminoglycans on glia and neuralprogenitors | |
| Meeting Hall I | |
| Chairs: | Larry Sherman (USA), Stephen Back (USA) |
| Speakers: | Larry Sherman (USA) - Hyaluronan catabolism in neural progenitor cell differentiation and remyelination failure |
| Stephen Back (USA) - Role of hyaluronan in the injured perinatal and elderly brain | |
| Jerry Silver (USA) - Roles of chondroitin sulfate in CNS injury | |
| Andreas Faissner (Germany) - Role of proteoglycans in neural progenitor cell differentiation | |
| Symposium 8 – Stem cells for the treatment of spinal cord injury: advances and controversies | |
| Forum Hall | |
| Chairs: | Michael Fehlings (Canada), James Fawcett (UK) |
| Speakers: | Pavla Jendelova (Czech Republic) - Stem cells and biomaterials for the treatment of spinal cord injury |
| Michael Fehlings (Canada) - Use of neural stem cells for repair of the injured spinal cord | |
| James Fawcett (UK) - Integration of transplanted glial cells into the damaged CNS | |
| Jack Price (UK) - Neural stem cells from human spinal cord as potential therapies and as models of disease | |
| 17.30 - 18.00 | Break |
| 18.00 - 19.00 | Plenary lecture 2 |
| Forum Hall | |
| Introduced by Ken McCarthy (USA) | |
| William D. Richardson (UK) – NG2-glia in myelin development, plasticity and repair | |
| 19:00 - 19:30 | Opening Address - Eva Syková - History of Czech Sciences |
| Opening Ceremony | |
| 19:30 - 21:30 | Welcome Reception |
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Thursday 15.9. 2011 |
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| 9.00 - 10.00 | Plenary lecture 3 |
| Forum Hall | |
| Introduced by Miroslava Anderova (Czech Republic) | |
| Vittorio Gallo (USA) - Gliogenesis and glial regeneration in the developing and adult brain: molecular mechanisms that promote functional repair | |
| 10.00 - 10.30 | Coffee break |
| 10.30 - 12.30 | Symposium 9 – Astrocytes: friend and foe in CNS pathology |
| Forum Hall | |
| Chairs: | Arthur Butt (UK), Jose Julio Rodriguez Arellano (Spain) |
| Speakers: | Arthur Butt (UK) - ATP and astrocyte pathophysiology |
| Jose Julio Rodriguez Arellano (Spain) - Astrocytes and Alzheimer's disease | |
| Sue Barnett (UK) - Functional duality of astrocytes in myelination | |
| Florence Perrin (Spain) - Astrocytes in spinal cord injury: towards clinical application | |
| Symposium 10 – Steroid signaling on glia: functional consequences | |
| Meeting Hall IV | |
| Chairs: | Arpad Parducz (Hungary), Roberto Melcangi (Italy) |
| Speakers: | Guy Mensah-Nyagan (France) - Neuron-glia cross-talk for neurosteroid production and regulatory effect in dorsal root ganglion |
| Luis Miguel Garcia Segura (Spain) - Regulation of reactive astrogliosis by estrogenic compounds | |
| Arpad Parducz (Hungary) - 17β-estradiol and selective estrogen receptor modulators attenuate injury-induced microglia activation in the oculomotor nucleus | |
| Roberto Melcangi (Italy) - In search for innovative tools for neuroprotection: sex- specific neuroprotective therapies based on neuroactive steroids | |
| Symposium 11 – Microglial clearance function in health and disease | |
| Panorama Hall | |
| Chairs: | Amanda Sierra (USA), Harald Neumann (Germany) |
| Speakers: | Bruce Carter (USA) - The phagocytic receptor Jedi signals engulfment through the tyrosine kinase Syk |
| Amanda Sierra (USA) - Microglial phagocytosis shapes adult hippocampal neurogenesis | |
| Bente Finsen (Denmark) - Microglial phagocytic functions in inflammation and pathological ageing | |
| Harald Neumann (Germany) - Microglial clearance in neurodegenerative diseases | |
| Symposium 12 – The vanilloid and cannabinoid system controls neural stem cell physiology and pathology | |
| Meeting Hall I | |
| Chairs: | Rainer Glass (Germany), Michael Synowitz (Germany) |
| Speakers: | Vincenzo Di Marzo (Italy) - The concept of endovanilloid and endocannabinoid signaling in the brain |
| Ismael Galve-Roperh (Spain) - Cannabinoid signaling in neurogenic stem cell niches | |
| Michael Synowitz (Germany) - Distinct roles for endovanilloid-signaling in neural precursor cells in physiology and pathology | |
| Rainer Glass (Germany) - Neural precursor cells induce primary brain tumor cell-death via stimulation of TRPV1 | |
| Workshop 2 - Neuroinflammatory reaction of peripheral glial cells following nerve injury - conditions for both axon regeneration and neuropathic pain induction | |
| Meeting Hall V | |
| Chairs: | Petr Dubovy (Czech Republic), Maria Abbracchio (Italy) |
| Speakers: | Petr Dubovy (Czech Republic) - Neuroinflammatory reaction of peripheral glial cells in experimental models of neuropathic pain based on nerve injury |
| Nurcan Uceyler (Germany) - Cellular and molecular key players inducing neuropathic pain after peripheral nerve injury | |
| Luc Jasmin (USA) - Glutamatergic transmission in the sensory ganglion: what is the evidence and how it contributes to neuropathic pain | |
| Maria Abbracchio (Italy) - Purinergic neuron/glia communication in trigeminal ganglia: interactions with other algogens and implications for migraine pain | |
| 12.30 - 13.30 | Lunch break |
| 13.00 - 14.00 | Special lecture - The GLIA Publishing Lecture |
| Forum Hall | |
| Bruce Ransom (USA) - Successful scientific publishing | |
| 13.30 - 15.30 | Poster Session/Exhibition |
| 15.00 - 15.30 | Coffee break |
| 15.30 - 17.30 | Symposium 13 – Targeting glia cells in the pathogenesis of Alzheimer’s disease: toward future therapeutic applications |
| Forum Hall | |
| Chairs: | Marianne Schultzberg (Sweden), Illana Gozes (Israel) |
| Speakers: | Illana Gozes (Israel) - Neuroprotective therapeutic application in Alzheimer’s disease: from glial proteins to drug candidates |
| Marianne Schultzberg (Sweden) - Cytokine and growth factor production by a human microglial cell line: effects of beta-amyloid | |
| Bogdan Popescu (Romania) - Overexpression of tight junction proteins in glial cells in Alzheimer's disease and vascular dementia | |
| Dan Frenkel (Israel) - Gamma-secretase component presenilin is important for microglia beta-amyloid clearance | |
| Symposium 14 – Teaching old dogs new tricks: CNS-specific functions for classic chemokines and cytokines | |
| Meeting Hall IV | |
| Chairs: | Tammy Kielian (USA), Monica Carson (USA) |
| Speakers: | Erik Boddeke (Netherlands) - The role of lymphoid chemokine ligands for CXCR3 in regulating glial function |
| Monica Carson (USA) - The role of CNS-produced CCL21 in CNS infection and autoimmune epilepsy | |
| Marco Prinz (Germany) - The role of type I interferons in maintaining brain homeostasis | |
| Tammy Kielian (USA) - Impact of MyD88 and the inflammasome on cytokine production by CNS-intrinsic cells during bacterial infection | |
| Symposium 15 – Acquiring a double-edged sword phenotype – phagocytic microglia | |
| Meeting Hall I | |
| Chairs: | Sandra Ribes (Germany), Uwe-Karsten Hanisch (Germany) |
| Speakers: | Uwe-Karsten Hanisch (Germany) - Microglia: How versatile are their responses, how heterogeneous are they to start with? |
| Shlomo Rotshenker (Israel) - Phagocytosis of degenerated myelin and its regulation by the cytoskeleton and the interaction between immune inhibitory receptor SIRPa and its ligand CD47 | |
| Sandra Ribes (Germany) - Phagocytosis of pathogens by stimulated murine microglia | |
| Jari Koistinaho (Finland) - Phagocytosis of beta-amyloid by mouse and human monocytic cells | |
| Symposium 16 – New insights on connexin and pannexin functions in neuroglial interactions | |
| Panorama Hall | |
| Chairs: | Nathalie Rouach (France), Eliana Scemes (USA) |
| Speakers: | Klaus Willecke (Germany) - Biological functions of gap junctional coupling between glia cells |
| Ken McCarthy (USA) - Genetic examination of the role of connexin 43 in neuronal astrocytic interactions during development | |
| Nathalie Rouach (France) - Deciphering the role of connexin 30 in synaptic transmission and plasticity | |
| Eliana Scemes (USA) - Role of pannexin1 in status epilepticus | |
| Workshop 3 - Proteolytic enzymes in gliomagenesis and neurodegeneration | |
| Meeting Hall V | |
| Chairs: | Jan Konvalinka (Czech Republic), Aleksi Sedo (Czech Republic) |
| Speakers: | Jan Konvalinka (Czech Republic) - Glutamate carboxypeptidase II and metabolism of N-acetyl-aspartyl-glutamate |
| Rolf Mentlein (Germany) - Proteases involved in glioma invasion | |
| Hans-Ulrich Demuth (Germany) - Glutaminyl Cyclases novel targets for the treatment of reactive gliosis and neurodegeneration in Alzheimer's disease | |
| Aleksi Sedo (Czech Republic) - Dipeptidyl peptidase-IV in gliomagenesis | |
| 17.30 - 18.00 | Break |
| 18.00 - 19.00 | Plenary lecture 4 |
| Forum Hall | |
| Introduced by Alex Verkhratsky (UK) | |
| Frank Kirchhoff (Germany) - Genetic mouse models and imaging approaches to study neuron-glia interactions in vivo | |
| 20.30 | Special event (by invitation only) |
| Martinicky palace | |
| WILEY-BLACKWELL Reception | |
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Friday 16.9. 2011 |
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| 9.00 - 10.00 | Plenary lecture 5 |
| Forum Hall | |
| Introduced by Helmut Kettenmann (Germany) | |
| Harry Sontheimer (USA) - Glial derived brain tumors: Unique biology and opportunities for novel treatments | |
| 10.00 - 10.30 | Coffee break |
| 10.30 - 12.30 | Symposium 17 – Endogenous remyelination: pathways for future therapies in multiple sclerosis? |
| Forum Hall | |
| Chairs: | Fernando de Castro (Spain), Robin Franklin (UK) |
| Speakers: | Robin Franklin (UK) - Phamacological targets for inducing oligodendrocyte differentiation during remyelination |
| Catherine Lubetzki (France) - Guidance cues and oligodendrocyte precursor cells recruitment after demyelination | |
| Hans Lassmann (Austria) - Remyelination failure in MS: the lessons from pathology | |
| Fernando de Castro (Spain) - FGF-2 and Anosmin-1 in Multiple Sclerosis: actors in pathology, targets for therapy? | |
| Symposium 18 – Regulation of glial Kir4.1 channels under physiological and pathophysiological conditions | |
| Meeting Hall V | |
| Chairs: | Gerald Seifert (Germany), Karl Kafitz (Germany) |
| Speakers: | Gerald Seifert (Germany) - Unravelling the molecular identity of potassium channels expressed by hippocampal astrocytes |
| Paulo Kofuji (USA) - Glial Kir4.1 channel: lessons from knockout models and human diseases | |
| Serguei Skatchkov (Puerto Rico) - Impact of glial Kir4.1 channels on glutamate uptake in astrocytes | |
| Karl Kafitz (Germany) - Role of Kir4.1 channels in ammonia-induced astroglial depolarization in the mouse hippocampus | |
| Symposium 19 – 3D neural cell culture – using tissue-like microenvironments to model normal and pathological neural/glial cell behaviours | |
| Panorama Hall | |
| Chairs: | Jane Loughlin (UK), Luc Stoppini (Switzerland) |
| Speakers: | Jane Loughlin / James Phillips (UK) - Monitoring glial cell behaviour and neuron-glial interactions in 3D hydrogel and aggregate culture systems |
| Luc Stoppini (Switzerland) - 3D in vitro engineered nervous tissue derived from mouse and human embryonic stem cells | |
| Omolara Ogunshola (Switzerland) - The blood-brain barrier in a dish: A new in vitro 3D model | |
| Michelle LaPlaca (USA) - Brain in a dish: Possibilities for the next generation of 3-D neural cultures | |
| Symposium 20 – Intrinsic determinants of microglial cell behaviour and function | |
| Meeting Hall I | |
| Chairs: | Iain Campbell (Australia), Jennifer Pocock (UK) |
| Speakers: | Etty Benveniste (USA) - Contribution of Myeloid Suppressor Of Cytokine Signaling 3 to the Development of Neuroinflammation |
| Jennifer Pocock (UK) - p53-activated pathways in microglia: good or bad for the brain? | |
| Iain Campbell (Australia) - IRF8 is a key determinant of microglial cell form and function | |
| Thomas Langmann (Germany) - Microglia in retinal degeneration: PU.1 and Egr1 control polarized transcriptional phenotypes | |
| 12.30 - 13.30 | Lunch break |
| 13.00 - 15.00 | Special event (by invitation only) |
| Room 2.2 | |
| GLIA Business Meeting | |
| 13.30 - 15.30 | Poster Session/Exhibition |
| 15.00 - 15.30 | Coffee break |
| 15.30 - 17.30 | Symposium 21 – Subventricular zone astrocytes and neurogenesis |
| Forum Hall | |
| Chairs: | Elly Hol (Netherlands), Angelique Bordey (USA) |
| Speakers: | Elly Hol (Netherlands) - Neurogenic astrocytes in the human subventricular zone in health and disease |
| Angelique Bordey (USA) - Identity and function of the slow cycling stem cell astrocytes | |
| Jose Manuel Garcia Verdugo (Spain) - How different looks the SVZ from mice to humans? | |
| Abdel Benraiss (USA) - Induced neurogenesis from the adult SVZ as a therapeutic strategy in Huntington's Disease | |
| Symposium 22 – Noradrenergic regulation of glial activation and inflammation | |
| Meeting Hall I | |
| Chairs: | Douglas Feinstein (USA), Michael Heneka (Germany) |
| Speakers: | Thomas Connor (Ireland) - Targeting glial beta2-adrenoceptors to drive an anti-inflammatory and neuroprotective environment in the CNS |
| Jose Munoz Madrigal (Spain) - Noradrenergic upregulation of CCL2/MCP-1 expression in astrocytes: a new mechanism of neuroprotection | |
| Douglas Feinstein (USA) - Locus coeruleus damage in EAE and MS | |
| Michael Heneka (Germany) - The role of the LC in AD: effects on glial cell activation and phagocytosis | |
| Symposium 23 – The role of glia and stem cells in cognitive and psychiatric disorders | |
| Panorama Hall | |
| Chairs: | John Bethea (USA), Mario Capecchi (USA) |
| Speakers: | Mario Capecchi (USA) - Bone marrow derived microglia and obsessive compulsive spectrum disorders |
| Amelia Eisch (USA) - New horizon for new neurons: adult hippocampal neurogenesis and psychiatric disorders | |
| John Bethea (USA) - Astroglial-NF-kB in learning and memory and neurogeneis: towards a better understanding on sex-linked neuropsychiatric and neurobehavioral disorders | |
| Renata Bartesaghi (Italy) - Widespread neurogenesis impairment during early brain development: a key determinant of neurological dysfunction in Down syndrome | |
| Symposium 24 – Neuro-glial-vascular signaling pathways in the brain | |
| Meeting Hall V | |
| Chairs: | Jessica Filosa (USA), Dale Pelligrino (USA) |
| Speakers: | Serge Charpak (France) - Is functional hyperaemia a reliable marker of glutamate release? |
| Dale Pelligrino (USA) - Purinergic mechanisms in gliovascular coupling | |
| Sergey Kasparov (UK) - Regional differences in astrocyte - neuronal signalling in the brainstem | |
| Jessica Filosa (USA) - Perivascular astrocytes as sensors and modulators of hemodynamics and neuronal activity in the brain | |
| 17.30 - 18.00 | Break |
| 18.00 - 19.00 | Plenary lecture 6 |
| Forum Hall | |
| Introduced by Eva Sykova (Czech Republic) | |
| Ole Petter Ottersen (Norway) - Glial water channels: new insight in the physiological and pathophysiological roles of AQP4 | |
| 20.30 - 23.00 | Special event (by invitation / purchased ticket only) |
| (Kaiserstejnsky palace) | |
| Meeting dinner | |
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Saturday 17.9. 2011 |
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| 9.00 - 10.00 | Plenary lecture 7 |
| Forum Hall | |
| Introduced by Vladimir Parpura (USA) | |
| Magdalena Götz (Germany) - Neurogenesis from glial cells – from neural stem cells to reactive gliosis and reprogramming | |
| 10.00 - 10.30 | Coffee break |
| 10.30 - 12.30 | Symposium 25 – Remyelination in multiple sclerosis – can we wrap it up? |
| Forum Hall | |
| Chairs: | Mark Kotter (UK), Christine Stadelmann-Nessler (Germany) |
| Speakers: | Christine Stadelmann-Nessler (Germany) - New insights in the pathology of MS lesions |
| Mark Kotter (UK) - MS lesion specific inhibitors of oligodendrocyte precursor cell differentiation | |
| Ben Emery (Australia) - Transcriptional regulation of CNS (re-)myelination | |
| Patrick Kuery (Germany) - Stimulating oligodendrocyte precursor cell differentiation in multiple sclerosis | |
| Symposium 26 – Glial aquaporins | |
| Panorama Hall | |
| Chairs: | Olivera Nesic (USA), Mahmood Amiry-Moghaddam (Norway) |
| Speakers: | Mahmood Amiry-Moghaddam (Norway) - Glial aquaporins: an overview |
| Eli Gunnarson (Sweden) - Water, sodium and potassium homeostasis in astrocytes: role in health and disease | |
| Antonio Frigeri (Italy) - Supramolecular organization of Aquaporin-4 into orthogonal array of particles as a key element for Neuromyelitis optica antibody binding | |
| Olivera Nesic (USA) - Aquaporins - novel players in spinal cord injury | |
| Symposium 27 – Regulation of astroglial glutamate transporters in health and disease | |
| Meeting Hall I | |
| Chairs: | Emmanuel Hermans (Belgium), Davide Trotti (USA) |
| Speakers: | Emmanuel Hermans (Belgium) - Regulation of astroglial glutamate transporters in the corpus callosum of transgenic rats developing amyotrophic lateral sclerosis ALS |
| Davide Trotti (USA) - Sumoylation of the glutamate transporter eaat2 and its implications for motor neuron degeneration in ALS | |
| Marcus Rattray (UK) - Regulation of GLT-1/EAAT2 at the cell surface | |
| Jeffrey Rothstein (USA) - Neuron-glial regulation of synaptic transporters - dysfunction and target for therapy | |
| Symposium 28 – Glial cells as targets for infectious agents in the human brain: acute and persistent outcomes | |
| Meeting Hall V | |
| Chairs: | Eugene Major (USA), Adriano Aguzzi (Switzerland) |
| Speakers: | Eugene Major (USA) - Human brain derived multipotential progenitor cells allows investigation of factors important for neurotropic virus infection |
| Adriano Aguzzi (Switzerland) - Neurotoxicity and clearance of prions | |
| Ruth Brack Werner (Germany) - Astrocytes and glial progenitor cells as long-term hosts of the human immunodoficiency virus (HIV) | |
| Jialin Zheng (USA) - HIV infection interferes with brain progenitor cells differentiation | |
| 12.30 - 13.30 | Lunch break |
| 13.30 - 15.30 | Poster Session/Exhibition |
| 15.00 - 15.30 | Coffee break |
| 15.30 - 17.30 | Symposium 29 – REST/NRSF: a master factor not only in neurons but also in glial cells (International Society for Neurochemistry Symposium) |
| Meeting Hall I | |
| Chairs: | Jacopo Meldolesi (Italy), Paola Bezzi (Switzerland) |
| Speakers: | Kiniki Nakashima (Japan) - BMP-induced REST/NRSF regulates the establishment and maintenance of astrocyte identity |
| Paola Bezzi (Switzerland) - REST/NRSF governs the expression of dense-core vesicle gliosecretion in astrocytes | |
| Joel M. Levine (USA) - REST function in the developing oligodendrocyte Lineage | |
| Jacopo Meldolesi (Italy) - Astrocyte structural plasticity governed by REST/NRSF via the expression of exocytic/endocytic vesicles | |
| Symposium 30 – Vesicle dynamics and exocytosis in astrocytes | |
| Panorama Hall | |
| Chairs: | Robert Zorec (Slovenia), Vladimir Parpura (USA) |
| Speakers: | Alfonso Araque (Spain) - Role of astrocytes in endocannabinoid - mediated synaptic plasticity |
| Vladimir Parpura (USA) - Spatio-temporal characteristics of exocytosis in astrocytes | |
| Jean-Pierre Mothet (France) - Vesicular transport of D-serine in astrocytes is coupled to serine racemase activity | |
| Robert Zorec (Slovenia) - Physiopathologic vesicle traffic and regulated exocytosis in astrocytes | |
| Symposium 31 – New role of glia in pain signaling | |
| Meeting Hall V | |
| Chairs: | Kazuhide Inoue (Japan), Ru-Rong Ji (USA) |
| Speakers: | Makoto Tsuda (Japan) - Microglia in pain signaling |
| Ru-Rong Ji (USA) - Astrocyte signaling in neuropathic pain | |
| Simon Beggs (Canada) - Glial regulation of synaptic transmission in pain | |
| Kazuhide Inoue (Japan) - Eco-Pharma in glial medicine against neuropathic pain | |
| Symposium 32 – Microglia in neuroinflammation and neurodegeneration | |
| Forum Hall | |
| Chairs: | Jeffrey Bajramovic (Netherlands), Trevor Owens (Denmark) |
| Speakers: | Jack Antel (Canada) - Distinct immune-regulatory properties of human microglia |
| Trevor Owens (Denmark) - Regulation by microglia of immune responses in the CNS | |
| Jeffrey Bajramovic (Netherlands) - Modulation of microglial activation by adenosine receptors | |
| Marina Lynch (Ireland) - Modulating microglial activation impacts on neuronal function | |
| 17.30 - 18.00 | Break |
| 18.00 - 19.00 | Plenary lecture 8 |
| Forum Hall | |
| Introduced by Bruce Ransom (USA) | |
| Christian Giaume (France) – Contribution of astroglial connexins to neuroglial and gliovascular interactions | |
| 19.00 - 19.30 | Closing remarks |
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